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Article

Phase Transitions Drive the Formation of Vesicular Stomatitis Virus Replication Compartments

5 Sept 2018

Abstract excerpt

RNA viruses compartmentalize their replication machinery to evade detection by host pattern recognition receptors and concentrate the machinery of RNA synthesis. For positive-strand RNA viruses, RNA replication occurs in a virus-induced membrane-associated replication organelle. For NNS RNA viruses, the replication compartment is a cytoplasmic inclusion that is not circumscribed by a cellular membrane. Such...

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PMID: 30181255
DOI: 10.1128/mbio.02290-17

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