Article
Novel MEIS1-NCOA2 Gene Fusions Define a Distinct Primitive Spindle Cell Sarcoma of the Kidney.
The American journal of surgical pathology - 1 Nov 2018
Argani Pedram, Reuter Victor E, Kapur Payal, Brown James E, Sung Yun-Shao, Zhang Lei, Williamson Richard, Francis Glen, Sommerville Scott, Swanson David, Dickson Brendan C, Antonescu Cristina R
Abstract excerpt
We describe 2 cases of a distinct sarcoma characterized by a novel MEIS1-NCOA2 gene fusion. This gene fusion was identified in the renal neoplasms of 2 adults (21-y-old male, 72-y-old female). Histologically, the resected renal neoplasms had a distinctively nodular appearance, and while one renal neoplasm was predominantly cystic, the other demonstrated solid architecture, invasion of perirenal fat, and renal...
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