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Article

Novel PAX3-NCOA1 Fusions in Biphenotypic Sinonasal Sarcoma With Focal Rhabdomyoblastic Differentiation.

The American journal of surgical pathology - 1 Jan 2016

Huang Shih-Chiang, Ghossein Ronald A, Bishop Justin A, Zhang Lei, Chen Tse-Ching, Huang Hsuan-Ying, Antonescu Cristina R

Abstract excerpt

Sarcomas arising in the sinonasal region are uncommon and encompass a wide variety of tumor types, including the newly described biphenotypic sinonasal sarcoma (BSNS), which is characterized by a monomorphic spindle cell proliferation with dual neural and myogenic phenotypes. Most BSNSs harbor a pathognomonic PAX3-MAML3 fusion driven by t(2;4)(q35;q31.1), whereas the alternative fusion partner gene remains...

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Source

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Identifiers

PMID: 26371783
DOI: 10.1097/PAS.0000000000000492
PMCID: PMC4679641

Genes

PAX3
NCOA1
MAML3
SOX10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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