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ZFP64::NCOA3 gene fusion defines a novel subset of spindle cell rhabdomyosarcoma

6 May 2022

Abstract excerpt

Spindle cell rhabdomyosarcoma represents a rare neoplasm characterized by monomorphic spindle cells with a fascicular architecture and variable skeletal muscle differentiation. Following incidental identification of a ZFP64::NCOA3 gene fusion in an unclassified spindle cell sarcoma resembling adult-type fibrosarcoma, we performed a retrospective archival review and identified four additional cases with a similar...

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PMID: 35521817
DOI: 10.1002/gcc.23052

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