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Article

Immunohistochemical expression of melanocytic and myofibroblastic markers and their molecular correlation in atypical fibroxanthomas and pleomorphic dermal sarcomas.

Journal of cutaneous pathology - 1 Dec 2018

Helbig Doris, Mauch Cornelia, Buettner Reinhard, Quaas Alexander

Abstract excerpt

BACKGROUND: Atypical fibroxanthomas (AFXs) and pleomorphic dermal sarcomas (PDSs) are UV-induced pleomorphic skin tumors with a non-specific immunoprofile. For that reason, exclusion of other dedifferentiated tumor entities by immunohistochemistry is still mandatory to avoid misdiagnosis. METHODS: We determined the expression frequency of several melanocytic and myofibroblastic markers investigating 50 AFXs and...

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Identifiers

PMID: 30155964
DOI: 10.1111/cup.13346

Genes

PDGFRA
SOX10

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