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Article

A preliminary assessment of Toll-like receptor and β-defensin gene polymorphisms in Papua New Guinea - what does it mean for HIV/AIDS?

Papua and New Guinea medical journal - 1 Jan 2000

Willie Barne, Gare Janet, King Christopher L, Zimmerman Peter A, Mehlotra Rajeev K

Abstract excerpt

Polymorphisms in Toll-like receptor (TLR) and human β-defensin (hBD, encoded by DEFB) genes have been evaluated for their associations with HIV infection and disease outcomes. Those studies, conducted in various populations under a variety of study designs, generally revealed that specific single nucleotide polymorphisms (SNPs) in TLR1, 2, 3, 4, 6, 7, 8, and 9 genes, and copy number variation (CNV) in DEFB4...

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beta-Defensins
DNA Copy Number Variations
Gene Frequency
TLR1 gene
HIV Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Papua New Guinea

Polymorphism, Single Nucleotide

Toll-Like Receptors

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Open in PubMed Open full text

Identifiers

PMID: 30147152
PMCID: PMC6105279

Genes

TLR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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