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Article

Associations between Variants in BDNF/BDNFOS Gene and Lumbar Disc Herniation Risk among Han Chinese People.

Scientific reports - 24 Aug 2018

Zhu Yong, Jia Haiyu, Li Jiabin, Ren Shaodong, Huang Zhi, Li Feng, Xing Wenhua, Li Shunan, Yang Xuejun

Abstract excerpt

Lumbar disc herniation (LDH) is a low back pain disorder and associated with several single nucleotide polymorphisms (SNPs). However, the role of brain-derived neurotrophic factor (BDNF) and BDNFOS gene in LDH susceptibility remains unknown. To examine whether the variants contribute to LDH, 7 SNPs were genotyped in 380 patients and 692 healthy controls among Han Chinese population. Multiple genetic models,...

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Identifiers

PMID: 30143695
DOI: 10.1038/s41598-018-31146-6
PMCID: PMC6109184

Genes

BDNF

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