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Mechanism of Cepharanthine Cytotoxicity in Human Ovarian Cancer Cells

24 Aug 2018

Abstract excerpt

Abstract Cepharanthine (CEP), a medicinal product derived from Stephania cephalantha Hayata, possesses a potent cytotoxicity against several types of cancers. Recently, we have found that CEP could efficiently inhibit the growth of mutated p53 colon cancer cells, which are often resistant to commonly used chemotherapeutic agents. In this study, we evaluated the cytotoxic effect and the underlying mechanisms of...

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PMID: 30142661
DOI: 10.1055/a-0706-7503

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