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Potent antitumor activity of cepharanthine against triple‑negative breast cancer spheroids compared with tetrandrine

6 Oct 2020

Abstract excerpt

Cepharanthine (CEP) is a bis‑bynzelisoquinoline alkaloid from the same class as the anticancer agent tetrandrine (TET). However, the effects of CEP against breast cancer have not been extensively studied, despite its long therapeutic history with low toxicity against other types of cancer. 3D culture systems more accurately mimic the human body and address the limitations of determining drug effectiveness...

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PMID: 33101499
DOI: 10.3892/ol.2020.12191

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