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Intracellular Pathways Involved in Bone Regeneration Triggered by Recombinant Silk–Silica Chimeras

4 Sept 2017

Abstract excerpt

. Recombinant silk-silica fusion peptides are organic-inorganic hybrid material systems that can be effectively used to study and control biologically-mediated mineralization due to the genetic basis of sequence control. However, to date, the mechanisms by which these functionalized silk-silica proteins trigger the differentiation of human mesenchymal stem cells (hMSCs) to osteoblasts remain unknown. To address...

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PMID: 30140193
DOI: 10.1002/adfm.201702570

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