Article
X-ray repair cross-complementing group 4 (XRCC4) promoter -1394( *)T-related genotype, but not XRCC4 codon 247/intron 3 or xeroderma pigmentosum group D codon 312, 751/promoter -114, polymorphisms are correlated with higher susceptibility to myoma.
Fertility and sterility - 1 Oct 2008
Hsieh Yao-Yuan, Chang Chi-Chen, Bau Da-Tian, Yeh Lian-Shen, Tsai Fuu-Jen, Tsai Chang-Hai
Abstract excerpt
OBJECTIVE: To investigate whether the DNA repair genes, X-ray repair cross-complementing group 4 (XRCC4) and xeroderma pigmentosum group D (XPD), could be useful markers for predicting leiomyoma susceptibility. DESIGN: Prospective study. SETTING: Departments of gynecology and genetics in medical center. PATIENT(S): Women were divided into leiomyoma (n = 120) and nonleiomyoma groups (n = 112). INTERVENTION(S):...
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