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Article

DNA repair gene XRCC1 Arg399Gln polymorphism is associated with increased risk of uterine leiomyoma.

Human reproduction (Oxford, England) - 1 Jun 2005

Jeon Yong-Tark, Kim Jae Weon, Park Noh-Hyun, Song Yong-Sang, Kang Soon-Beom, Lee Hyo-Pyo

Abstract excerpt

BACKGROUND: DNA repair gene XRCC1 Arg399Gln polymorphism has been associated with the risk of several human tumours. In the present study we investigated whether the XRCC1 polymorphism is related to the risk of uterine leiomyoma, the most common neoplasm of the female genital tract. METHODS: Three hundred and twenty-seven patients with uterine leiomyoma and 197 normal controls were enrolled, and XRCC1 genotyping...

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Source

Identifiers

PMID: 15760950
DOI: 10.1093/humrep/deh836

Genes

XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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DNA repair gene XRCC1 Arg399Gln polymorphism is associated with increased risk of uterine leiomyoma.PMID 15760950Read ↗

Genetic polymorphisms of DNA repair gene XRCC1 and risk of uterine leiomyoma.Semantic proximity Read ↗

A meta-analysis of XRCC1 single nucleotide polymorphism and susceptibility to gynecological malignancies.Semantic proximity Read ↗

Contribution of X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3) Genotype to Leiomyoma Risk.Semantic proximity Read ↗

The p21 codon 31*C- and DRD2 codon 313*T-related genotypes/alleles, but not XRCC1 codon 399, hOGG1 codon 326, and DRD1-48 polymorphisms, are correlated with the presence of leiomyoma.Semantic proximity Read ↗

XPG rs873601 G>A contributes to uterine leiomyoma susceptibility in a Southern Chinese population.Semantic proximity Read ↗

New Concept of X-Ray Repair Cross-Complementing Groups 1 Polymorphisms and Gynecologic Cancer Risk.Semantic proximity Read ↗

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