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Article

MiR-122 inhibits epithelial mesenchymal transition by regulating P4HA1 in ovarian cancer cells.

Cell biology international - 1 Nov 2018

Duan Yanan, Dong Yinghui, Dang Rongguang, Hu Zhihui, Yang Ye, Hu Yueyun, Cheng Jianxin

Abstract excerpt

Ovarian cancer is one of the most common gyneacologic malignancies, with high morbidity and high mortality. Hsa-miR-122-5p (miR-122) has been reported with tumor-suppressing roles in various cancers. In this study, miR-122 was overexpressed in ovarian cancer cells, and phenotypic experiments demonstrated that miR-122 inhibited migration and invasion in SKOV3 and OVCAR3 cells. MiR-122 also suppressed epithelial...

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Identifiers

PMID: 30136751
DOI: 10.1002/cbin.11052

Genes

MMP14

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