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Article

High miR-122 expression promotes malignant phenotypes in ccRCC by targeting occludin.

International journal of oncology - 1 Jul 2017

Jingushi Kentaro, Kashiwagi Yuri, Ueda Yuko, Kitae Kaori, Hase Hiroaki, Nakata Wataru, Fujita Kazutoshi, Uemura Motohide, Nonomura Norio, Tsujikawa Kazutake

Abstract excerpt

Renal cell carcinoma (RCC) is the most common neoplasm of the adult kidney, and clear cell RCC (ccRCC) represents its most common histological subtype. Although several studies have reported high expression of miR-122 in ccRCC, its physiological role remains unclear. To clarify the role of miR-122 in ccRCC, we compared miR-122 expression levels in non-cancerous tissue and ccRCC. Significant upregulation of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28534944
DOI: 10.3892/ijo.2017.4016

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