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Article

Retinoic acid signaling is essential for airway smooth muscle homeostasis

22 Aug 2018

Abstract excerpt

Airway smooth muscle (ASM) is a dynamic and complex tissue involved in regulation of bronchomotor tone, but the molecular events essential for the maintenance of ASM homeostasis are not well understood. Observational and genome-wide association studies in humans have linked airway function to the nutritional status of vitamin A and its bioactive metabolite retinoic acid (RA). Here, we provide evidence that...

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PMID: 30135301
DOI: 10.1172/jci.insight.120398

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