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Article

PPAR<i>γ</i>Signaling Mediates the Evolution, Development, Homeostasis, and Repair of the Lung

1 Jan 2012

Abstract excerpt

Epithelial-mesenchymal interactions mediated by soluble growth factors determine the evolution of vertebrate lung physiology, including development, homeostasis, and repair. The final common pathway for all of these positively adaptive properties of the lung is the expression of epithelial parathyroid-hormone-related protein, and its binding to its receptor on the mesenchyme, inducing PPARγ expression by...

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PMID: 22792087
DOI: 10.1155/2012/289867

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