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Article

Brain-derived neurotrophic factor in human subjects with function-altering melanocortin-4 receptor variants.

International journal of obesity (2005) - 1 Aug 2014

Hohenadel M G, Thearle M S, Grice B A, Huang H, Dai M-H, Tao Y-X, Hunter L A, Palaguachi G I, Mou Z, Kim R C, Tsang M M, Haack K, Voruganti V S, Cole S A, Butte N F, Comuzzie A G, Muller Y L, Baier L J, Krakoff J, Knowler W C, Yanovski J A, Han J C

Abstract excerpt

BACKGROUND: In rodents, hypothalamic brain-derived neurotrophic factor (BDNF) expression appears to be regulated by melanocortin-4 receptor (MC4R) activity. The impact of MC4R genetic variation on circulating BDNF in humans is unknown. OBJECTIVE: The objective of this study is to compare BDNF con...

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Source

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Identifiers

PMID: 24276017
DOI: 10.1038/ijo.2013.221
PMCID: PMC4033711

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24276017-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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