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The tetraspanin CD82 regulates bone marrow homing and engraftment of hematopoietic stem and progenitor cells

22 Aug 2018

Abstract excerpt

Hematopoietic stem and progenitor cell (HSPC) transplantation represents a treatment option for patients with malignant and nonmalignant hematological diseases. Initial steps in transplantation involve the bone marrow homing and engraftment of peripheral blood-injected HSPCs. In recent work, we identified the tetraspanin CD82 as a potential regulator of HSPC homing to the bone marrow, although its mechanism...

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PMID: 30133344
DOI: 10.1091/mbc.e18-05-0305

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