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Article

Epigenetic alterations of CYLD promoter modulate its expression in gastric adenocarcinoma: A footprint of infections.

Journal of cellular physiology - 1 Apr 2019

Ghadami Elham, Nikbakhsh Novin, Fattahi Sadegh, Kosari-Monfared Mohadeseh, Ranaee Mohammad, Taheri Hassan, Amjadi-Moheb Fatemeh, Godazandeh Gholamali, Shafaei Shahryar, Nosrati Anahita, Pilehchian Langroudi Maryam, Samadani Ali Akbar, Amirbozorgi Galia, Mirnia Vahideh, Akhavan-Niaki Haleh

Abstract excerpt

Gastric cancer (GC) is one of the most common causes of cancer-related death in the world, with multiple genetic and epigenetic alterations involved in disease development. CYLD tumor suppressor gene encodes a multifunctional deubiquitinase which negatively regulates various signaling pathways. Deregulation of this gene has been found in different types of cancer. This study aimed to evaluate for the first time...

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Identifiers

PMID: 30132887
DOI: 10.1002/jcp.27220

Genes

CYLD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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