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Expression, DNA methylation pattern and transcription factor EPB41L3 in gastric cancer: a study of 262 cases

1 Oct 2024

Abstract excerpt

DNA methylation prominently inactivates tumor suppressor genes and facilitates oncogenesis. Previously, we delineated a chromosome 18 deletion encompassing the erythrocyte membrane protein band 4.1-like 3 (EPB41L3) gene, a progenitor for the tumor suppressor that is differentially expressed in adenocarcinoma of the lung-1 (DAL-1) in gastric cancer (GC). Our current investigation aimed to elucidate EPB41L3...

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PMID: 39354571
DOI: 10.1186/s12964-024-01849-7

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