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Article

Intratumor lactate levels reflect HER2 addiction status in HER2‐positive breast cancer

21 Aug 2018

Abstract excerpt

Despite different molecular tumor profiles indicate that human epidermal growth factor receptor 2 (HER2) messenger RNA (mRNA) levels mirror HER2 addiction and trastuzumab benefit in HER2-positive breast cancer (BC), the identification of noninvasive clinical predictors of trastuzumab sensitivity remains an unmet clinical need. In the current study, we investigated whether intratumor lactate levels reflect HER2...

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PMID: 30132876
DOI: 10.1002/jcp.27049

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