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Methylation‐independent ITGA2 overexpression is associated with poor prognosis in de novo acute myeloid leukemia

21 Aug 2018

Abstract excerpt

Previous studies have been indicated that integrin α2 (ITGA2) may be important in cell migration, invasion, survival, and angiogenesis. However, the correlation between ITGA2 expression and acute myeloid leukemia (AML) is still unclear. Real‐time quantitative polymerase chain reaction was carried out to analyze ITGA2 messenger RNA level. Methylation‐specific polymerase chain reaction (PCR) and bisulfite...

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PMID: 30132837
DOI: 10.1002/jcp.26866

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