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Article

Whole-genome sequencing and single nucleotide polymorphisms in multidrug-resistant clinical isolates of Mycobacterium tuberculosis from the Philippines.

Journal of global antimicrobial resistance - 1 Dec 2018

Roa Marylette B, Tablizo Francis A, Morado El King D, Cunanan Lovette F, Uy Iris Diana C, Ng Kamela Charmaine S, Manalastas-Cantos Karen G, Reyes Joeriggo M, Ganchua Sharie Keanne C, Ang Concepcion F, Kato-Maeda Midori, Cattamanchi Adithya, Karaoz Ulas, Destura Raul V, Lluisma Arturo O

Abstract excerpt

OBJECTIVES: Thousands of cases of multidrug-resistant tuberculosis (TB) have been observed in the Philippines, but studies on the Mycobacterium tuberculosis (MTB) genotypes that underlie the observed drug resistance profiles are lacking. This study aimed to analyse the whole genomes of clinical MTB isolates representing various resistance profiles to identify single nucleotide polymorphisms (SNPs) in...

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PMID: 30130640
DOI: 10.1016/j.jgar.2018.08.009

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