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Article

CTLA-4 and PD-1 Ligand Gene Expression in Epithelial Thyroid Cancers

5 Jul 2018

Abstract excerpt

The dysregulation of PD-1 ligands (PD-L1 and PD-L2) and CTLA-4 ligands (CD80 and CD86) represents a tumor strategy to escape the immune surveillance. Here, the expression of PD-L1, PD-L2, CD80, and CD86 was evaluated at the mRNA level in 94 patients affected by papillary thyroid carcinoma (PTC) and 11 patients affected by anaplastic thyroid carcinoma (ATC). Variations in the mRNAs in PTC patients were then...

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Identifiers

PMID: 30123257
DOI: 10.1155/2018/1742951

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