Article
Identification of risk loci for postpartum depression in a genome-wide association study.
Psychiatry and clinical neurosciences - 1 Nov 2024
Li Xue, Takahashi Nagahide, Narita Akira, Nakamura Yukako, Sakurai-Yageta Mika, Murakami Keiko, Ishikuro Mami, Obara Taku, Kikuya Masahiro, Ueno Fumihiko, Metoki Hirohito, Ohseto Hisashi, Takahashi Ippei, Nakamura Tomohiro, Warita Noriko, Shoji Tomoka, Yu Zhiqian, Ono Chiaki, Kobayashi Natsuko, Kikuchi Saya, Matsuki Tasuku, Nagami Fuji, Ogishima Soichi, Sugawara Junichi, Hoshiai Tetsuro, Saito Masatoshi, Fuse Nobuo, Kinoshita Kengo, Yamamoto Masayuki, Yaegashi Nobuo, Ozaki Norio, Tamiya Gen, Kuriyama Shinichi, Tomita Hiroaki
Abstract excerpt
AIM: Genome-wide association studies (GWAS) of postpartum depression (PPD) based on accumulated cohorts with multiple ethnic backgrounds have failed to identify significantly associated loci. Herein, we conducted a GWAS of Japanese perinatal women along with detailed confounding information to uncover PPD-associated loci. METHODS: The first and second cohorts (n = 9260 and n = 8582 perinatal women enrolled in the...
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