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Article

MMP-2: is too low as bad as too high in the cardiovascular system?

American journal of physiology. Heart and circulatory physiology - 1 Nov 2018

Hardy Eugenio, Hardy-Sosa Anette, Fernandez-Patron Carlos

Abstract excerpt

Matrix metalloproteinase (MMP)-2 cleaves a broad spectrum of substrates, including extracellular matrix components (responsible for normal tissue remodeling) and cytokines (modulators of the inflammatory response to physiological insults such as tissue damage). MMP-2 expression is elevated in many cardiovascular pathologies (e.g., myocardial infarction, hypertensive heart disease) where tissue remodeling and...

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Identifiers

PMID: 30118342
DOI: 10.1152/ajpheart.00198.2018

Genes

MMP2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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