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Article

Down-regulation of let-7a and miR-21 in urine exosomes from lupus nephritis patients during disease flare

1 Aug 2018

Abstract excerpt

BACKGROUND: The contents of exosomes determine their biological functions and represent a new class of epigenetic modulation of renal cells considering as novel class of biomarker. OBJECTIVE: Our study aims to investigate the expression of microRNAs (miRNA), including miR-10a/b, let-7a, and miR-21, in urinary exosomes isolated from patients with active lupus nephritis (LN) compared to inactive LN. METHODS: The...

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PMID: 30118248
DOI: 10.12932/ap-130318-0280

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