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Article

MicroRNAs in Lupus Nephritis–Role in Disease Pathogenesis and Clinical Applications

4 Oct 2021

Abstract excerpt

MicroRNAs (miRs) are non-coding small RNAs that act as epigenetic modulators to regulate the protein levels of target mRNAs without modifying the genetic sequences. The role of miRs in the pathogenesis of lupus nephritis (LN) is increasingly recognized and highly complex. Altered levels of different miRs are observed in the blood, urine and kidney tissues of murine LN models and LN patients. Accumulating evidence...

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PMID: 34639078
DOI: 10.3390/ijms221910737

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