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Epigenetic regulation of macrophage function in kidney disease: New perspective on the interaction between epigenetics and immune modulation

13 Jan 2025

Abstract excerpt

The interaction between renal intrinsic cells and macrophages plays a crucial role in the onset and progression of kidney diseases. In recent years, epigenetic mechanisms such as DNA methylation, histone modification, and non-coding RNA regulation have become essential windows for understanding these processes. This review focuses on how renal intrinsic cells (including tubular epithelial cells, podocytes, and...

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PMID: 39809127
DOI: 10.1016/j.biopha.2025.117842

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