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Lupus nephritis: The regulatory interplay between epigenetic and MicroRNAs

16 Sept 2022

Abstract excerpt

MicroRNAs (miRNAs) are endogenous, small, non-coding RNA molecules that act as epigenetic modifiers to regulate the protein levels of target messenger RNAs without altering their genetic sequences. The highly complex role of miRNAs in the epigenetics of lupus nephritis (LN) is increasingly being recognized. DNA methylation and histone modifications are focal points of epigenetic research. miRNAs play a critical...

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PMID: 36187762
DOI: 10.3389/fphys.2022.925416

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