Article
An imbalance in the T-helper phenotypes displayed by senescent CD4+CD28null T cells is associated with erosive arthritis (rhupus syndrome) in systemic lupus erythematosus.
Lupus - 1 Nov 2018
Lozada-Navarro A C, Castillo-Martínez D, Moreno-Ramírez M, Acosta-Peña G, Páez A, Massó F, Márquez-Velasco R, Amezcua-Guerra L M
Abstract excerpt
OBJECTIVE: The objective was to assess the proportion of Th1, Th2 and Th17 phenotypes in senescent CD4+CD28null cells from patients with systemic lupus erythematosus (SLE) and its association with the pattern of joint involvement. METHODS: This cross-sectional study was performed in SLE patients with erosive arthritis (rhupus) or nondeforming, nonerosive arthritis. Total CD4+CD28null cells as well as the...
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