Article
Decreased Th17 and Th1 cells in the peripheral blood of patients with early non-radiographic axial spondyloarthritis: a marker of disease activity in HLA-B27⁺ patients.
Rheumatology (Oxford, England) - 1 Feb 2013
Bautista-Caro María-Belén, Arroyo-Villa Irene, Castillo-Gallego Concepción, de Miguel Eugenio, Peiteado Diana, Puig-Kröger Amaya, Martín-Mola Emilio, Miranda-Carús María-Eugenia
Abstract excerpt
OBJECTIVE: To examine the frequency and phenotype of Th17 cells in the peripheral blood of patients with early non-radiographic axial SpA (early nrSpA). METHODS: CD4(+) T cells were isolated from the peripheral blood of 30 early nrSpA patients, 11 AS patients and 41 age- and sex-matched healthy controls by Ficoll-Hypaque gradient and magnetic negative selection. After polyclonal stimulation, the frequency of Th17...
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