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Article

Comprehensive Genomic Profiling of Hodgkin Lymphoma Reveals Recurrently Mutated Genes and Increased Mutation Burden.

The oncologist - 1 Feb 2019

Liang Winnie S, Vergilio Jo-Anne, Salhia Bodour, Huang Helen J, Oki Yasuhiro, Garrido-Laguna Ignacio, Park Haeseong, Westin Jason R, Meric-Bernstam Funda, Fabrizio David, Miller Vincent A, Stephens Philip J, Fanale Michelle A, Ross Jeffrey S, Janku Filip

Abstract excerpt

BACKGROUND: The genomic landscape of Hodgkin lymphoma (HL) has been difficult to characterize due to the paucity of neoplastic cells and an abundant microenvironment. Such characterization is needed in order to improve treatment strategies. MATERIALS AND METHODS: We performed comprehensive genomic profiling (CGP) using targeted next-generation sequencing on archival formalin-fixed paraffin embedded tumor samples...

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Identifiers

PMID: 30108156
DOI: 10.1634/theoncologist.2018-0058
PMCID: PMC6369943

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XPO1

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