Article
Vitamin D receptor (VDR) gene polymorphism and vascular dementia due to cerebral small vessel disease in an Asian Indian cohort.
Journal of the neurological sciences - 15 Aug 2018
Supriya Manjunath, Chandra Sadanandavalli Retnaswami, Prabhakar Puttachandra, Prasad Chandrajit, Christopher Rita
Abstract excerpt
Vitamin D receptor (VDR) and its ligand Vitamin D, play a crucial role in regulating multiple pathways for maintaining vascular health. The present study aimed at evaluating whether single nucleotide polymorphisms in VDR gene were associated with susceptibility to vascular dementia (VaD) due to cerebral small vessel disease (SVD). A total of 644 subjects (302 patients diagnosed with cerebral SVD-associated VaD...
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