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PIMMS43 is required for malaria parasite immune evasion and sporogonic development in the mosquito vector

12 Mar 2020

Abstract excerpt

After being ingested by a female Anopheles mosquito during a bloodmeal on an infected host, and before they can reach the mosquito salivary glands to be transmitted to a new host, Plasmodium parasites must establish an infection of the mosquito midgut in the form of oocysts. To achieve this, they must first survive a series of robust innate immune responses that take place prior to, during, and immediately after...

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PMID: 32165544
DOI: 10.1073/pnas.1919709117

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