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Article

A novel genetic marker of decreased inflammation and improved survival after acute myocardial infarction.

Basic research in cardiology - 10 Aug 2018

Coverstone Edward D, Bach Richard G, Chen LiShiun, Bierut Laura J, Li Allie Y, Lenzini Petra A, O'Neill Heidi C, Spertus John A, Sucharov Carmen C, Stitzel Jerry A, Schilling Joel D, Cresci Sharon

Abstract excerpt

The CHRNA5 gene encodes a neurotransmitter receptor subunit involved in multiple processes, including cholinergic autonomic nerve activity and inflammation. Common variants in CHRNA5 have been linked with atherosclerotic cardiovascular disease. Association of variation in CHRNA5 and specific haplotypes with cardiovascular outcomes has not been described. The aim of this study was to examine the association of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 30097758
DOI: 10.1007/s00395-018-0697-7
PMCID: PMC6292447

Genes

CHRNA5

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