Association of Desmin Gene Variant rs1058261 with Cardiovascular Disease, the TAMRISK Study.

doi:10.1089/gtmb.2018.0118

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Association of Desmin Gene Variant rs1058261 with Cardiovascular Disease, the TAMRISK Study.

Genetic testing and molecular biomarkers - 1 Sept 2018

Piesanen Jaakko, Kunnas Tarja, Nikkari Seppo T

Abstract excerpt

AIMS: Since desmin expression is diminished in vascular smooth muscle cells during reparative processes, we wanted to study whether a common intragenic single nucleotide polymorphism at nucleotide position 828 (rs1058261) of the DES gene associates with hypertension, cerebrovascular complications, and all cardiovascular events in the Tampere adult population cardiovascular risk (TAMRISK) study. MATERIALS AND...

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PMID: 30096250
DOI: 10.1089/gtmb.2018.0118

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