Genetic and clinicopathologic characteristics of lung adenocarcinoma with tumor spread through air spaces.

doi:10.1016/j.lungcan.2018.07.020

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Article

Genetic and clinicopathologic characteristics of lung adenocarcinoma with tumor spread through air spaces.

Lung cancer (Amsterdam, Netherlands) - 1 Sept 2018

Lee Jae Seok, Kim Eun Kyung, Kim Moonsik, Shim Hyo Sup

Abstract excerpt

OBJECTIVE: The World Health Organization Classification of Lung Tumors considers "Spread Through Air Spaces (STAS)" as a form of invasion in lung adenocarcinoma. However, its existence as an independent pathologic entity rather than an artifact caused by spreading through a knife surface is still controversial. Therefore, we performed comprehensive analyses on the genetic and clinicopathologic characteristics of...

Topics

Adenocarcinoma of Lung
Adult
Aged
Biomarkers, Tumor
Female
Genetic Association Studies
Genetic Variation
Humans
Male
Middle Aged
Neoplasm Invasiveness
Neoplasm Metastasis
Neoplasm Staging
Prognosis
Recurrence
Survival Analysis
Tumor Burden

Source

Open in PubMed

Identifiers

PMID: 30089582
DOI: 10.1016/j.lungcan.2018.07.020

Genes

EGFR
ALK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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