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Article

Tumor islands in resected early-stage lung adenocarcinomas are associated with unique clinicopathologic and molecular characteristics and worse prognosis.

The American journal of surgical pathology - 1 Feb 2013

Onozato Maristela L, Kovach Alexandra E, Yeap Beow Y, Morales-Oyarvide Vicente, Klepeis Veronica E, Tammireddy Swathi, Heist Rebecca S, Mark Eugene J, Dias-Santagata Dora, Iafrate A John, Yagi Yukako, Mino-Kenudson Mari

Abstract excerpt

Tumor islands-large collections of tumor cells isolated within alveolar spaces-can be seen in lung adenocarcinomas. Recently we observed by 3-dimensional reconstruction that these structures were connected with each other and with the main tumor in different tissue planes, raising the possibility...

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Identifiers

PMID: 23095504
DOI: 10.1097/PAS.0b013e31826885fb
PMCID: PMC3545070

Genes

EGFR
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23095504-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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