Article
Degradation of selenoprotein S and selenoprotein K through PPARγ-mediated ubiquitination is required for adipocyte differentiation.
Cell death and differentiation - 1 Jun 2019
Lee Jea Hwang, Jang Jun Ki, Ko Kwan Young, Jin Yunjung, Ham Minju, Kang Hyunwoo, Kim Ick Young
Abstract excerpt
Adipocyte differentiation is known to be related with endoplasmic reticulum (ER) stress. We have reported that selenoprotein S (SelS) and selenoprotein K (SelK) have a function in the regulation of ER stress and ER-associated degradation. However, the association between adipocyte differentiation and the ER-resident selenoproteins, SelS and SelK, is unclear. In this study, we found that the levels of SelS and...
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