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Article

FOXP2 Targets Show Evidence of Positive Selection in European Populations

18 Apr 2013

Abstract excerpt

Forkhead box P2 (FOXP2) is a highly conserved transcription factor that has been implicated in human speech and language disorders and plays important roles in the plasticity of the developing brain. The pattern of nucleotide polymorphisms in FOXP2 in modern populations suggests that it has been the target of positive (Darwinian) selection during recent human evolution. In our study, we searched for evidence of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 23602712
DOI: 10.1016/j.ajhg.2013.03.019

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