Article
EHP-101, an oral formulation of the cannabidiol aminoquinone VCE-004.8, alleviates bleomycin-induced skin and lung fibrosis.
Biochemical pharmacology - 1 Nov 2018
García-Martín Adela, Garrido-Rodríguez Martín, Navarrete Carmen, Del Río Carmen, Bellido María L, Appendino Giovanni, Calzado Marco A, Muñoz Eduardo
Abstract excerpt
Systemic sclerosis (SSc) or scleroderma is a chronic multi-organ autoimmune disease characterized by vascular, immunological, and fibrotic abnormalities. The etiology of SSc is unknown, but there is growing evidence that dysfunction of the endocannabinoid system (ECS) plays a critical role in its development. Since the semi-synthetic cannabinoquinoid VCE-004.8 could alleviate bleomycin (BLM)-induced skin...
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