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Article

Induced pluripotent stem cell line from an atopic dermatitis patient heterozygous for c.2282del4 mutation in filaggrin: KCLi001-A.

Stem cell research - 1 Aug 2018

Devito Liani, Donne Matthew, Kolundzic Nikola, Khurana Preeti, Hobbs Carl, Kaddour Gabriel, Dubrac Sandrine, Gruber Robert, Schmuth Matthias, Mauro Thea, Ilic Dusko

Abstract excerpt

We have generated an induced pluripotent stem cell (iPSC) line KCLi001-A (iOP118) from a female atopic dermatitis (AD) patient, heterozygous for the loss-of-function mutation c.2282del4 in the filaggrin gene (FLG). Epidermal keratinocytes were reprogrammed using non-integrating Sendai virus vectors. The entire process of derivation and expansion of AD-iPSCs were performed under xeno-free culture conditions....

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Dermatitis, Atopic
Filaggrin Proteins
FLG gene
Heterozygote
Induced Pluripotent Stem Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Intermediate Filament Proteins

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Identifiers

PMID: 30075366
DOI: 10.1016/j.scr.2018.07.014
PMCID: PMC7514110

Genes

FLG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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