Article
Circular RNA ciRS-7 Maintains Metastatic Phenotypes as a ceRNA of miR-1299 to Target MMPs.
Molecular cancer research : MCR - 1 Nov 2018
Sang Meixiang, Meng Lingjiao, Liu Sihua, Ding Pingan, Chang Sheng, Ju Yingchao, Liu Fei, Gu Lina, Lian Yishui, Geng Cuizhi
Abstract excerpt
Circular RNA ciRS-7 has been reported to act as a competing endogenous RNA (ceRNA) of the miRNA miR-7, resulting in reduced miR-7 activity and increased miR-7-targeted transcripts. However, it is unknown if ciRS-7 harbors other miRNAs with regulatory roles in triple-negative breast cancer (TNBC). The present study determined that the expression of ciRS-7 in TNBC clinical specimens and representative cells is...
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