Article
Development of a circHIPK3-based ceRNA network and identification of mRNA signature in breast cancer patients harboring BRCA mutation.
PeerJ - 1 Jan 2023
Lian Qi-Xin, Song Yang, Han Lili, Wang Zunxian, Song Yinhui
Abstract excerpt
Background: Exploring the regulatory network of competing endogenous RNAs (ceRNAs) as hallmarks for breast cancer development has great significance and could provide therapeutic targets. An mRNA signature predictive of prognosis and therapy response in BRCA carriers was developed according to circular RNA homeodomain-interacting protein kinase 3 (circHIPK3)-based ceRNA network. Method: We constructed a...
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