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Article

Lipid nanoparticle siRNA cocktails for the treatment of mantle cell lymphoma

7 Mar 2018

Abstract excerpt

Abstract Mantle cell lymphoma is an aggressive and incurable subtype of non‐Hodgkin B cell lymphoma. Patients typically present with advanced disease, and most patients succumb within a decade of diagnosis. There is a clear and urgent need for novel therapeutic approaches that will affect mantle cell lymphoma through a unique mechanism compared to current therapies. This study examined the use of RNA interference...

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PMID: 30065968
DOI: 10.1002/btm2.10088

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