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Zika virus infects human testicular tissue and germ cells

31 Jul 2018

Abstract excerpt

Zika virus (ZIKV) is a teratogenic mosquito-borne flavivirus that can be sexually transmitted from man to woman. The finding of high viral loads and prolonged viral shedding in semen suggests that ZIKV replicates within the human male genital tract, but its target organs are unknown. Using ex vivo infection of organotypic cultures, we demonstrated here that ZIKV replicates in human testicular tissue and infects a...

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PMID: 30063220
DOI: 10.1172/jci121735

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