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Article

Infection of epididymal epithelial cells and leukocytes drives seminal shedding of Zika virus in a mouse model.

PLoS neglected tropical diseases - 1 Aug 2018

McDonald Erin M, Duggal Nisha K, Ritter Jana M, Brault Aaron C

Abstract excerpt

While primarily a mosquito-borne virus, Zika virus (ZIKV; genus Flavivirus in the Flaviviridae family) is capable of being sexually transmitted. Thirty to fifty percent of men with confirmed ZIKV infection shed ZIKV RNA in their semen, and prolonged viral RNA shedding in semen can occur for more than 6 months. The cellular reservoir of ZIKV in semen is unknown, although spermatozoa have been shown to contain ZIKV...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30070988
DOI: 10.1371/journal.pntd.0006691
PMCID: PMC6091970

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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