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Article

Structural determinants of Neosartorya fischeri antifungal protein (NFAP) for folding, stability and antifungal activity.

Scientific reports - 16 May 2017

Galgóczy László, Borics Attila, Virágh Máté, Ficze Hargita, Váradi Györgyi, Kele Zoltán, Marx Florentine

Abstract excerpt

The recent global challenges to prevent and treat fungal infections strongly demand for the development of new antifungal strategies. The structurally very similar cysteine-rich antifungal proteins from ascomycetes provide a feasible basis for designing new antifungal molecules. The main structural elements responsible for folding, stability and antifungal activity are not fully understood, although this is an...

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Identifiers

PMID: 28512317
DOI: 10.1038/s41598-017-02234-w
PMCID: PMC5434006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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