Article

Modes of action and bio-fungicide potential of peptides derived from the bi-domain plant defensin MtDef5

2024-12-22

Abstract excerpt

Medicago truncatula bi-domain defensin MtDef5 exhibits antifungal activity at sub-micromolar concentrations against some fungal pathogens. It comprises two single-domain defensins, MtDef5A and MtDef5B, connected with a linker APKKVEP. MtDef5B is a more potent antifungal defensin than MtDef5A. We identified amino acid residues important for antifungal activity of MtDef5B and elucidated its modes of action (MoA). Mt...

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Literature Corpus work: 9ebe203a-fcad-5978-8e81-6c70bf4465ce
DOI: 10.1101/2024.12.20.629707

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